Leicester back rower Wainwright has proved Wales’ most effective forward ball-carrier in recent times.
He picked up a minor calf injury against Japan and has spent the week in a protective boot as he battles to be fit against Australia
Basham was recalled to the Wales squad after impressing for Cardiff.
His previous Wales appearance came as a replacement in the 2024 Six Nations against England, while his last international start came in the 2022 tournament against the same opposition.
It is only his second Test start at number eight.
“I’m delighted that Taine gets an opportunity this weekend,” said Tandy.
“It’s been a while since his last appearance for Wales but he didn’t give up and has put in a lot of dedication and hard work to get back.
“The way he’s been playing for Cardiff has been great and I’m excited to see him go on Saturday.”
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